sleep wake disorders

Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

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Study Counts

Type	Study_count
Total_Studies	314
interventional	230
Observational	78
Registry	6

Studies over Time by Start Date

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Interventional Trials

Intervention Type

intervention_type	Study_Count
Behavioral	55
Drug|placebo	49
Drug	32
Device	28
Other	24
Procedure	11
Behavioral|Other	7
Device|placebo	4
Dietary Supplement	3
Behavioral|Other|Procedure	2
Diagnostic Test	2
Dietary Supplement|placebo	2
Drug|Other|placebo	2
Other|Procedure	2
Behavioral|Procedure	1
Device|Drug	1
Drug|Other	1
Drug|Other|placebo|Procedure	1
Drug|Procedure	1
Genetic	1
Genetic|Other	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country	Study_Count
United States	114
NA	24
France	8
China	6
Germany	6
Switzerland	6
Taiwan	6
Brazil	4
Canada	4
Spain	4
Denmark	3
Greece	3
Italy	3
Norway	3
United States|Canada	3
Australia	2
Belgium	2
India	2
Korea, Republic of	2
Poland	2
Sweden	2
United States|Germany	2
Argentina	1
Croatia	1
Ecuador	1
Finland	1
Germany|Australia|Czech Republic|Finland|France|Netherlands|Switzerland|United Kingdom	1
Germany|Italy	1
Hong Kong	1
Ireland	1
Japan	1
Mexico	1
Netherlands	1
Romania	1
Turkey	1
United States|Australia|Canada|France|Germany|Puerto Rico|Russian Federation	1
United States|Australia|Canada|France|Korea, Republic of|United Kingdom	1
United States|Canada|Germany	1
United States|Finland|France|Netherlands|United Kingdom	1
United States|Israel|United Kingdom	1
United States|Russian Federation	1

Sites per Study

Site_count	Study_Count
1	184
2	10
3	3
4	4
5	4
6	4
8	1
11	2
12	1
13	2
15	2
20	1
22	2
28	2
33	1
42	1
50	2
51	1
62	1
94	1
100	1

Phase

Phase	Study_Count
N/A	143
Phase 3	30
Phase 2	22
Phase 4	21
Phase 1	8
Early Phase 1	2
Phase 1/Phase 2	2
Phase 2/Phase 3	2

Number of Arms

Number_of_Arms	Count_of_Studies
1	39
2	132
3	25
4	12
5	4
NA	18

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	22	1.0000	2.000	48.00	13.00000	66.0	20.000	5.00000
1st Qu.	24	35.0000	22.250	51.75	33.00000	98.5	86.000	20.00000
Median	26	60.0000	31.000	55.50	61.00000	131.0	136.000	40.00000
Mean	26	153.9718	31.875	55.50	86.68182	131.0	227.069	74.61905
3rd Qu.	28	107.2500	37.000	59.25	114.75000	163.5	259.000	86.00000
Max.	30	1836.0000	72.000	63.00	410.00000	196.0	876.000	312.00000

Trial Group Type

group_type	Group_Count
Experimental	220
Active Comparator	87
Placebo Comparator	70
No Intervention	30
Other	28
NA	18
Sham Comparator	11

Intervention Model

intervention_model	Study_Count
Parallel Assignment	142
Single Group Assignment	47
Crossover Assignment	30
Factorial Assignment	7
Sequential Assignment	2
NA	2

Primary Purpose

primary_purpose	Study_Count
Treatment	142
Supportive Care	26
Basic Science	14
Health Services Research	13
Prevention	12
Diagnostic	11
Other	7
Screening	2
NA	2
Device Feasibility	1

Observational Studies

Studies by Country

Country	Study_Count
United States	28
NA	6
France	5
Turkey	5
Germany	4
Canada	3
Italy	3
United Kingdom	3
China	2
Czechia	2
Israel	2
Poland	2
Switzerland	2
Belgium	1
Brazil	1
Denmark	1
Denmark|Germany|Portugal|Spain|Switzerland	1
Egypt	1
Korea, Republic of	1
Norway	1
Slovenia	1
Taiwan	1
United States|Canada|Germany|Israel	1
United States|Israel	1

Sites per Study

Site_count	Study_Count
1	67
2	4
3	1
4	1
10	1
15	1
24	1
201	1
1153	1

Enrollment Metrics

Measure	Observational
Min	6.0000
1st Qu	50.0000
Median	100.0000
Mean	623.0395
3rd Qu	300.0000
Max	10000.0000

Observation Model

observational_model	Study_Count
Cohort	41
NA	9
Case-Only	8
Case-Control	6
Other	6
Case Control	3
Family-Based	2
Case-Crossover	1
Defined Population	1
Ecologic or Community	1

Time Perspective

time_perspective	Study_Count
Prospective	46
Cross-Sectional	22
NA	4
Retrospective	3
Other	2
Cross-Sectional, Retrospective/Prospective	1

Registries

Studies by Country

Country	Study_Count
Denmark	2
Korea, Republic of	2
China	1
United States	1

Sites per Study

Site_count	Study_Count
1	5
15	1

Enrollment Metrics

Measure	Registries
Min	20.00
1st Qu	41.25
Median	172.50
Mean	217.50
3rd Qu	300.00
Max	600.00

Registry Model

observational_model	Study_Count
Cohort	3
Case-Control	2
Case-Only	1

Time Perspective

time_perspective	Study_Count
Prospective	4
Cross-Sectional	1
Other	1

Follow-up

target_duration	Study_Count
12 Months	1
2 Years	1
21 Months	1
30 Days	1
5 Years	1
6 Months	1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT04451668	An Open Label Study of FT218 in Subjects With Narcolepsy	https://ClinicalTrials.gov/show/NCT04451668	Recruiting	Avadel	2023-06-30
NCT03948152	A Study to Determine Preferences Towards Interface Products	https://ClinicalTrials.gov/show/NCT03948152	Completed	Philips Respironics	2020-02-07
NCT03823105	Validation of Non-invasive Miniature Optical Sensors for Scoring Sleep Stages	https://ClinicalTrials.gov/show/NCT03823105	Completed	University Hospital Inselspital, Berne	2020-04-01
NCT03344562	Cranial Electrical Stimulation (CES) as Treatment for Insomnia in Patients With Subacute Stroke	https://ClinicalTrials.gov/show/NCT03344562	Completed	University of Texas Southwestern Medical Center	2019-12-31
NCT03335904	AT1R Blockade and Periodic Breathing During Sleep in Hypoxia	https://ClinicalTrials.gov/show/NCT03335904	Active, not recruiting	University of British Columbia	2020-01-31
NCT03335527	Impacts of Low-Dose Dexmedetomidine on Sleep Quality in Mechanically Ventilated ICU Patients	https://ClinicalTrials.gov/show/NCT03335527	Completed	Peking University First Hospital	2019-10-31
NCT03326765	Characterizing Sleep Disorders in Children and Adults With Tuberous Sclerosis Complex (TSC)	https://ClinicalTrials.gov/show/NCT03326765	Recruiting	Universitair Ziekenhuis Brussel	2019-11-01
NCT03299114	WHIRLPOOL FOR OSTEOARHRITIS	https://ClinicalTrials.gov/show/NCT03299114	Completed	Ufuk University	2016-01-01
NCT03277027	Health Related Lifestyle and Quality of Life in Children With Cerebral Palsy	https://ClinicalTrials.gov/show/NCT03277027	Completed	The Catholic University of Korea	2018-05-10
NCT03210675	Early Detection and Treatment of Respiratory Sleep Disorders in Children With Down Syndrome	https://ClinicalTrials.gov/show/NCT03210675	Active, not recruiting	Institut Jerome Lejeune	2022-12-31
NCT03205033	Melatonin as a Circadian Clock Regulator, Neuromodulator and Myelo-protector in Adjuvant Breast Cancer Chemotherapy	https://ClinicalTrials.gov/show/NCT03205033	Completed	Hospital de Clinicas de Porto Alegre	2017-01-31
NCT03188718	WatchPAT Device Validation Study Compared to Polysomnography	https://ClinicalTrials.gov/show/NCT03188718	Completed	University of Colorado, Denver	2019-06-01
NCT03153917	Biological Rhythms Impact of 12 Hours Shift Work	https://ClinicalTrials.gov/show/NCT03153917	Completed	Hospices Civils de Lyon	2017-07-28
NCT03130803	Biomarkers of Insufficient Sleep and Sleepiness	https://ClinicalTrials.gov/show/NCT03130803	Completed	University of Colorado, Boulder	2019-02-22
NCT03110731	Effect of Strength Training on the Quality and Duration of Sleep and Daytime Sleepiness of Institutionalized Adolescents	https://ClinicalTrials.gov/show/NCT03110731	Completed	University of Pernambuco	2016-12-24
NCT03108599	Tech4Rest Trial With Team Truck Drivers	https://ClinicalTrials.gov/show/NCT03108599	Recruiting	Oregon Health and Science University	2021-09-30
NCT03075241	Z-Drugs for Sleep Disorders in Alzheimer’s Disease	https://ClinicalTrials.gov/show/NCT03075241	Recruiting	Brasilia University Hospital	2020-04-30
NCT03066518	Effect of Melatonin on Sleep Quality in Patients Dementia	https://ClinicalTrials.gov/show/NCT03066518	Completed	Hospital Universitario Dr. Jose E. Gonzalez	2017-01-25
NCT03055156	Effect of High Rebound Mattress Toppers on Sleep and Sleep-Related Symptoms	https://ClinicalTrials.gov/show/NCT03055156	Completed	Stanford University	2019-10-31
NCT03018912	Validating the Use of a Subjectively Reported Sleep Vital Sign	https://ClinicalTrials.gov/show/NCT03018912	Recruiting	Kaiser Permanente	2021-01-31
NCT02978053	Light Treatment to Shift-working Nurses	https://ClinicalTrials.gov/show/NCT02978053	Completed	University of Bergen	2019-06-30
NCT02961400	Improving Memory for Sleep Treatment Content With Text Messages	https://ClinicalTrials.gov/show/NCT02961400	Completed	University of California, Berkeley	2017-12-31
NCT02957383	Evning Exposure to Computer Screen Disrupts Sleep, Attention and Biological Rhythms	https://ClinicalTrials.gov/show/NCT02957383	Completed	Assuta Medical Center	2016-03-31
NCT02939586	The Effect of Haemodialysis in Sleep Apnoea	https://ClinicalTrials.gov/show/NCT02939586	Completed	John Hunter Hospital	2018-10-01
NCT02922439	Health Literacy Assessment and Intervention to Reduce Disparities: FLIGHT/VIDAS II	https://ClinicalTrials.gov/show/NCT02922439	Recruiting	Nova Southeastern University	2021-03-31
NCT02773693	Treatment of Comorbid Sleep Disorders and Post Traumatic Stress Disorder (PTSD)	https://ClinicalTrials.gov/show/NCT02773693	Active, not recruiting	University of North Texas, Denton, TX	2019-09-30
NCT02757079	Study of the Efficacy and Safety of NPC-15 for Sleep Disorders of Children With Neurodevelopmental Disorders	https://ClinicalTrials.gov/show/NCT02757079	Completed	Nobelpharma	2018-07-31
NCT02757066	Verification of the Efficacy of NPC-15 for Sleep Disorders of Children With Autism Spectrum Disorders	https://ClinicalTrials.gov/show/NCT02757066	Completed	Nobelpharma	2018-09-30
NCT02731677	Acupuncture as Adjuvant Therapy for Sleep Disorders in Parkinson’s Disease	https://ClinicalTrials.gov/show/NCT02731677	Completed	Universidade Federal de Pernambuco	2016-02-29
NCT02660385	Insomnia Self-Management in Heart Failure	https://ClinicalTrials.gov/show/NCT02660385	Active, not recruiting	Yale University	2020-06-30
NCT02637297	Hypnotherapy in Treating Chronic Pain in Cancer Survivors	https://ClinicalTrials.gov/show/NCT02637297	Completed	Fred Hutchinson Cancer Research Center	2017-02-09
NCT02541747	Assessments in Stress and Quality of Sleep/Life in Night-shift Nurses and Doctors	https://ClinicalTrials.gov/show/NCT02541747	Completed	Taichung Veterans General Hospital	2015-06-30
NCT02523079	Cognitive Behavioral Therapy for Insomnia Among Different Types of Shift Workers	https://ClinicalTrials.gov/show/NCT02523079	Active, not recruiting	Finnish Institute of Occupational Health	2019-12-31
NCT02507089	Tailored Approach to Sleep Health Education: A Community Engaged Approach	https://ClinicalTrials.gov/show/NCT02507089	Completed	NYU Langone Health	2017-12-31
NCT02484963	The Study of Spectrum of Sleep Disorders in Cirrhotic Patients and the Efficacy of Zolpidem in Cirrhotic Patients With Insomnia	https://ClinicalTrials.gov/show/NCT02484963	Completed	Institute of Liver and Biliary Sciences, India	2017-01-15
NCT02477527	Atripla to Stribild Switch Study to Evaluate Sleep Disturbances	https://ClinicalTrials.gov/show/NCT02477527	Completed	Midtown Medical Center, Tampa, FL	2015-12-31
NCT02403492	Treatment of Obstructive Sleep Apnea in Children: An Opportunity for Cardiovascular Risk Modification	https://ClinicalTrials.gov/show/NCT02403492	Completed	The Hospital for Sick Children	2015-08-31
NCT02374918	Bright Light Therapy for Treatment of Sleep Problems Following Mild Traumatic Brain Injury	https://ClinicalTrials.gov/show/NCT02374918	Completed	University of Arizona	2019-09-30
NCT02321826	Music for Insomnia	https://ClinicalTrials.gov/show/NCT02321826	Completed	University of Aarhus	2017-09-29
NCT02240849	Effectiveness of Functional Pillow on Neck Pain, Disability, Quality of Sleep and Life	https://ClinicalTrials.gov/show/NCT02240849	Completed	Jaseng Hospital of Korean Medicine	2014-09-30
NCT02199847	Evaluation of the Effects of Pharmaton Tablets on Mental Performance and Physical Fatigue in Nurses Working Night Shift	https://ClinicalTrials.gov/show/NCT02199847	Completed	Boehringer Ingelheim	2001-01-31
NCT02198989	Effects of Peer Support and Yoga Music on T2DM With Depression and Sleep Disorders	https://ClinicalTrials.gov/show/NCT02198989	Completed	Shanghai Jiao Tong University School of Medicine	2014-10-31
NCT02192333	Survivorship Care in Reducing Symptoms in Young Adult Cancer Survivors	https://ClinicalTrials.gov/show/NCT02192333	Active, not recruiting	Fred Hutchinson Cancer Research Center	2017-10-07
NCT02156128	Subjective Memory Complaints, Objective Memory Performance and Cognitive Training	https://ClinicalTrials.gov/show/NCT02156128	Completed	Norwegian University of Science and Technology	2015-03-31
NCT02132273	Use of an Educational Story to Prepare Children With Developmental Disabilities for Sleep Study	https://ClinicalTrials.gov/show/NCT02132273	Completed	Hugo W. Moser Research Institute at Kennedy Krieger, Inc.	2016-06-30
NCT02130999	Open Label Study to Assess the Absolute Bioavailability of Tasimelteon (HETLIOZâ„¢)	https://ClinicalTrials.gov/show/NCT02130999	Completed	Vanda Pharmaceuticals	2014-05-31
NCT02108353	Circadian Phase Adjustment and Improvement of Metabolic Control in Night Shift Workers	https://ClinicalTrials.gov/show/NCT02108353	Completed	Universitätsklinikum Hamburg-Eppendorf	2017-03-29
NCT02095496	Efficacy of Closed-loop Ventilation to Reduced Sleep Disorders	https://ClinicalTrials.gov/show/NCT02095496	Completed	Cliniques universitaires Saint-Luc- Université Catholique de Louvain	2015-12-31
NCT02061514	The Effect of Two Different General Anesthesia Regimes on Postoperative Sleep Quality	https://ClinicalTrials.gov/show/NCT02061514	Recruiting	Aretaieion University Hospital	2020-12-31
NCT01317329	“Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved”	https://ClinicalTrials.gov/show/NCT01317329	Completed	University of Wisconsin, Madison	2014-09-30
NCT01299597	A Single-centre Open Label Study to Investigate the Effect of Repeat Doses of SB-649868 on the Pharmacokinetics of Simvastatin and Atorvastatin in Healthy Male Volunteers.	https://ClinicalTrials.gov/show/NCT01299597	Completed	GlaxoSmithKline	2010-02-26
NCT01289197	Health Promotion in Early Adolescence: Sleep, Activity, and Emotion Regulation	https://ClinicalTrials.gov/show/NCT01289197	Completed	University of Pittsburgh	2013-03-31
NCT01284140	Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients	https://ClinicalTrials.gov/show/NCT01284140	Completed	University of Iowa	2016-12-31
NCT02043977	Efficacy and Safety Study of Propofol Infusion for Refractory Chronic Primary Insomnia	https://ClinicalTrials.gov/show/NCT02043977	Completed	Life Extension Foundation Inc.	2015-05-31
NCT02037438	Sustainable Methods, Algorithms, and Research Tools for Delivering Optimal Care Study	https://ClinicalTrials.gov/show/NCT02037438	Completed	Stanford University	2016-05-31
NCT02491788	Examination of the Effectiveness of Suvorexant in Improving Daytime Sleep in Shift Workers	https://ClinicalTrials.gov/show/NCT02491788	Completed	VA Palo Alto Health Care System	2019-08-01
NCT04412941	Respiratory Rehabilitation in Obstructive Sleep Apneas	https://ClinicalTrials.gov/show/NCT04412941	Enrolling by invitation	Università degli Studi ‘G. d’Annunzio’ Chieti e Pescara	2020-09-30
NCT03356938	The Role of the Circadian System in Neurological Sleep-wake Disorders	https://ClinicalTrials.gov/show/NCT03356938	Recruiting	University of Zurich	2019-04-01
NCT02002533	Brief Behavioral Therapy in Improving Sleep Disorders in Patients With Stage I-III Breast Cancer Undergoing Chemotherapy	https://ClinicalTrials.gov/show/NCT02002533	Completed	University of Rochester	2016-12-16
NCT02025959	Sleep for Inpatients: Empowering Staff to Act	https://ClinicalTrials.gov/show/NCT02025959	Recruiting	University of Chicago	2020-08-31
NCT01993251	Does Melatonin Restore Sleep Architecture in Autistic Children	https://ClinicalTrials.gov/show/NCT01993251	Completed	Hospices Civils de Lyon	2018-06-12
NCT01988129	Fire Fighter Fatigue Management Program: Operation Healthy Sleep	https://ClinicalTrials.gov/show/NCT01988129	Completed	Brigham and Women’s Hospital	2013-09-30
NCT01929720	Cognitive-Behavioral Intervention for Worry, Uncertainty, and Insomnia for Cancer Survivors	https://ClinicalTrials.gov/show/NCT01929720	Completed	Ohio State University Comprehensive Cancer Center	2014-09-30
NCT01906866	Efficacy and Safety of Circadin® in the Treatment of Sleep Disturbances in Children With Neurodevelopment Disabilities	https://ClinicalTrials.gov/show/NCT01906866	Completed	Neurim Pharmaceuticals Ltd.	2018-03-27
NCT01877616	Sleep Disorders and Their Cardiovascular Correlates in Atahualpa.	https://ClinicalTrials.gov/show/NCT01877616	Completed	Hospital Clínica Kennedy	2013-10-31
NCT01809821	Sleep to Lower Elevated Blood Pressure	https://ClinicalTrials.gov/show/NCT01809821	Completed	University College Hospital Galway	2014-06-30
NCT01745497	Iron Treatment of Sleep Disorders in Children With Autism Spectrum Disorder	https://ClinicalTrials.gov/show/NCT01745497	Completed	University of Colorado, Denver	2015-08-31
NCT01672502	Fire Fighter Fatigue Management Program: Operation Fight Fatigue	https://ClinicalTrials.gov/show/NCT01672502	Completed	Brigham and Women’s Hospital	2014-05-31
NCT01626989	Evaluation of the Philips Respironics BiPAP autoSV Devices in Subjects With Sleep Disorders	https://ClinicalTrials.gov/show/NCT01626989	Completed	Philips Respironics	2012-06-30
NCT01557595	Blue Wavelength Light-blocking Glasses in ADHD-Insomnia	https://ClinicalTrials.gov/show/NCT01557595	Completed	University of Alabama at Birmingham	2012-06-30
NCT01536977	Phase II Early Behavioral Intervention in BMT w/ Sleep Disturbance-Assess QOL+Fatigue+Cognitive f(x)	https://ClinicalTrials.gov/show/NCT01536977	Completed	Stanford University	2013-09-30
NCT01534338	Effect of Mindfulness Training on Sleep and Inflammation Among Older Adults With Sleep Problems	https://ClinicalTrials.gov/show/NCT01534338	Completed	University of California, Los Angeles	2012-12-31
NCT01534130	Acupuncture for the Sleep Disorder of Chronic Fatigue Syndrome	https://ClinicalTrials.gov/show/NCT01534130	Completed	Chengdu University of Traditional Chinese Medicine	2012-08-31
NCT01468038	A Double-blind Placebo Controlled Trial of Sentra PM, a Medical Food	https://ClinicalTrials.gov/show/NCT01468038	Completed	Targeted Medical Pharma	2008-10-31
NCT01466270	Study of Donepezil in Female Breast Cancer Survivors With Cognitive Dysfunction	https://ClinicalTrials.gov/show/NCT01466270	Completed	Wake Forest University Health Sciences	2013-10-31
NCT01430754	Withdrawal Study to Demonstrate the Maintenance Effect in the Treatment of Non-24-Hour Sleep-Wake Disorder	https://ClinicalTrials.gov/show/NCT01430754	Completed	Vanda Pharmaceuticals	2012-12-31
NCT01429116	Tasimelteon for the Treatment of Non-24-hour Sleep-Wake Disorder (N24HSWD) in Blind Individuals With no Light Perception	https://ClinicalTrials.gov/show/NCT01429116	Completed	Vanda Pharmaceuticals	2015-01-31
NCT01427192	Treatment of Sleep Related Breathing Disorders in Patients With Pulmonary Hypertension	https://ClinicalTrials.gov/show/NCT01427192	Completed	University of Zurich	2012-12-31
NCT01405313	Modified Adaptive Servoventilation (ASV) Compared to Conventional ASV	https://ClinicalTrials.gov/show/NCT01405313	Completed	ResMed	2011-09-30
NCT01402570	Glutathione and Health With Post-Polio Syndrome	https://ClinicalTrials.gov/show/NCT01402570	Completed	University of Michigan	2013-04-30
NCT01342328	Providing “Good Sleep” for ICU Sedation	https://ClinicalTrials.gov/show/NCT01342328	Completed	University of California, San Francisco	2018-10-01
NCT01338649	Light Therapy Treatment in Parkinson’s Disease Patients With Daytime Somnolence	https://ClinicalTrials.gov/show/NCT01338649	Completed	Northwestern University	2012-10-31
NCT01327040	Light Sensitization Study	https://ClinicalTrials.gov/show/NCT01327040	Active, not recruiting	Brigham and Women’s Hospital	2015-12-31
NCT04407351	Develop Novel Phototherapy for Health Care of Patients With Sleep Disorder, Mild Cognitive Impairment, or Dementia	https://ClinicalTrials.gov/show/NCT04407351	Completed	Kaohsiung Medical University	2020-04-30
NCT04402619	Online Cognitive Behavior Therapy for Comorbid Sleep Problems in Alcohol Use Disorder	https://ClinicalTrials.gov/show/NCT04402619	Recruiting	Karolinska Institutet	2020-09-30
NCT04373538	Improving Well-being by Improving Memory for Treatment for Sleep and Circadian Dysfunction	https://ClinicalTrials.gov/show/NCT04373538	Recruiting	University of California, Berkeley	2020-12-31
NCT04354922	Different Exercising Intensities and Frequencies of Exercise on Depressive Mood and Insomnia	https://ClinicalTrials.gov/show/NCT04354922	Recruiting	The University of Hong Kong	2021-09-30
NCT04245761	Open Non-Comparative Study To Evaluate Administration Of a New Nutraceutical	https://ClinicalTrials.gov/show/NCT04245761	Completed	Italfarmaco	2019-05-24
NCT04219566	Vestibular Nerve Stimulation to Improve Sleep	https://ClinicalTrials.gov/show/NCT04219566	Recruiting	Neurovalens Ltd.	2020-08-31
NCT04210882	The Effects of Exercise on Sleep and Brain Health	https://ClinicalTrials.gov/show/NCT04210882	Recruiting	Massachusetts General Hospital	2020-10-31
NCT04157244	The Music, Sleep and Dementia Study	https://ClinicalTrials.gov/show/NCT04157244	Active, not recruiting	University of Pennsylvania	2021-06-10
NCT04154631	Implementing and Sustaining a Sleep Treatment to Improve Community Mental Health Outcomes	https://ClinicalTrials.gov/show/NCT04154631	Recruiting	University of California, Berkeley	2022-07-31
NCT04133350	Patients With Heart Failure With Preserved Ejection Fraction Adherence to ASV Therapy Pilot Registry (PEP ASV Pilot Registry)	https://ClinicalTrials.gov/show/NCT04133350	Recruiting	Thomas Jefferson University	2021-05-01
NCT04094376	Comparison of Morning Operation and Evening Operation on Postoperative Sleep Quality and Pain Under General Anesthesia	https://ClinicalTrials.gov/show/NCT04094376	Completed	Shengjing Hospital	2020-01-31
NCT04089397	Light Therapy on Sleep Quality in Dialysis Patients	https://ClinicalTrials.gov/show/NCT04089397	Recruiting	Centre Hospitalier Annecy Genevois	2020-05-11
NCT04087603	Teen Sleep Health Study	https://ClinicalTrials.gov/show/NCT04087603	Completed	Rush University Medical Center	2019-05-12
NCT04048785	The Effect of Sleep Intervention on Social-emotional Development in Early Childhood	https://ClinicalTrials.gov/show/NCT04048785	Recruiting	Shanghai Jiao Tong University School of Medicine	2020-12-31
NCT04000113	Therapeutic Effect of Laser Acupuncture on Insomnia in Perimenopausal Women	https://ClinicalTrials.gov/show/NCT04000113	Recruiting	Taipei Veterans General Hospital, Taiwan	2020-05-01
NCT03998020	Constitution of a Clinical, Neurophysiological and Biological Cohort for Chronic Sleep Disorders Responsible of Hypersomnolence	https://ClinicalTrials.gov/show/NCT03998020	Recruiting	University Hospital, Montpellier	2022-11-30
NCT03985228	Nutritional Trial With Probiotic Fortified Milk in Women Affected by Insomnia	https://ClinicalTrials.gov/show/NCT03985228	Completed	University of Bologna	2016-07-31
NCT03984058	Recruitment Strategies Comparing Different Strategies in Sleep Apnea and Prediabetes	https://ClinicalTrials.gov/show/NCT03984058	Recruiting	Johns Hopkins University	2020-11-30
NCT03933553	Effect of Easy Sleep Complex Essential Oil Inhalation on Sleep Disorders	https://ClinicalTrials.gov/show/NCT03933553	Recruiting	Kuang Tien General Hospital	2020-12-31
NCT03912571	Sleep Disordered Breathing and Alzheimer’s Disease Biomarkers in Normal Aging and Mild Cognitive Impairment	https://ClinicalTrials.gov/show/NCT03912571	Recruiting	NYU Langone Health	2019-09-30
NCT03897062	Suvorexant in the Management Comorbid Sleep Disorder and Alcohol Dependence	https://ClinicalTrials.gov/show/NCT03897062	Recruiting	The Florey Institute of Neuroscience and Mental Health	2020-12-31
NCT03881618	Efficacy of Electro-Acupuncture Therapy for Patients With Methadone Maintenance Treatment	https://ClinicalTrials.gov/show/NCT03881618	Recruiting	Taipei City Hospital	2018-12-31
NCT03879044	Transcranial Direct Current Stimulation Therapy for Sleepiness Related to Shift Work Disorder (tDCS-SWORD)	https://ClinicalTrials.gov/show/NCT03879044	Recruiting	Ohio State University	2021-03-19
NCT03857802	Efficiency of a Nursing Intervention in Sleep Hygiene	https://ClinicalTrials.gov/show/NCT03857802	Recruiting	Jordi Gol i Gurina Foundation	2019-04-30
NCT03855774	Polymorphisms, Caffeine and Sleep Disorders	https://ClinicalTrials.gov/show/NCT03855774	Completed	Institut de Recherche Biomedicale des Armees	2018-01-01
NCT03852966	Better Sleep in Psychiatric Care - ADHD	https://ClinicalTrials.gov/show/NCT03852966	Completed	Karolinska Institutet	2016-09-30
NCT03843645	General Versus Regional Anesthesia and Postoperative Sleep Quality	https://ClinicalTrials.gov/show/NCT03843645	Recruiting	Aretaieion University Hospital	2020-12-31
NCT03828656	NightWare Open Enrollment Study	https://ClinicalTrials.gov/show/NCT03828656	Enrolling by invitation	NightWare	2021-02-01
NCT03818581	Suvorexant on Sleep Disturbance in Patients With Chronic Insomnia and Suboptimally Controlled Type 2 Diabetes	https://ClinicalTrials.gov/show/NCT03818581	Recruiting	Massachusetts General Hospital	2021-03-15
NCT03813654	Sleep and Circadian Treatments for Shift Workers	https://ClinicalTrials.gov/show/NCT03813654	Recruiting	Brigham and Women’s Hospital	2022-12-31
NCT03788733	The Efficacy of Melatonin in the Burning Mouth Syndrome	https://ClinicalTrials.gov/show/NCT03788733	Recruiting	Universidad de Murcia	2019-06-14
NCT03768830	Impact of Exercise on “Invisible” Symptoms and Quality of Life in Multiple Sclerosis Individuals	https://ClinicalTrials.gov/show/NCT03768830	Completed	University of Rijeka	2019-02-05
NCT03758768	The Effects of a Blue Monochromatic Light Intervention on Evening-type Individuals’ Sleep and Circadian Rhythms	https://ClinicalTrials.gov/show/NCT03758768	Completed	University of Bergen	2018-10-22
NCT03734341	Comparison of Two Telemonitoring Auto-titrating Modalities in OSA Patients	https://ClinicalTrials.gov/show/NCT03734341	Completed	Basque Health Service	2018-09-01
NCT03731481	Virtual Lifestyle Medicine Comparative Effectiveness Research	https://ClinicalTrials.gov/show/NCT03731481	Completed	Ohio University	2018-02-28
NCT03727906	Sleep and Cardiovascular Health in Adolescence	https://ClinicalTrials.gov/show/NCT03727906	Recruiting	SRI International	2021-06-15
NCT03696654	High Blood Pressure in Paediatric Patients With Sleep Disorder Breathing.	https://ClinicalTrials.gov/show/NCT03696654	Recruiting	Fundacion del Hospital Nacional de Paraplejicos para la Investigacion y la Integracion	2020-11-01
NCT03682185	The Healthy Patterns Study	https://ClinicalTrials.gov/show/NCT03682185	Recruiting	University of Pennsylvania	2021-05-31
NCT03673397	The Acute Effect of Aerobic Exercise on Sleep in Patients With Depression	https://ClinicalTrials.gov/show/NCT03673397	Completed	Oberwaid AG	2020-01-06
NCT03636880	Heart Failure Insomnia Treatment Study	https://ClinicalTrials.gov/show/NCT03636880	Recruiting	Ohio State University	2020-05-31
NCT03617770	A Sleep Intervention in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03617770	Completed	University of Illinois at Chicago	2019-11-20
NCT03594851	Evaluation of the Benefits of Individualized Advice Administration on Quality of Sleep for the Elderly Living at Home	https://ClinicalTrials.gov/show/NCT03594851	Completed	Groupe Hospitalier de la Region de Mulhouse et Sud Alsace	2019-07-08
NCT03576664	Effects of Sleep Deprivation and Adrenergic Inhibition on Glymphatic Flow in Humans	https://ClinicalTrials.gov/show/NCT03576664	Completed	Rigshospitalet, Denmark	2019-09-01
NCT03568045	Feasibility Pilot of Bright Light in the Intensive Care Unit	https://ClinicalTrials.gov/show/NCT03568045	Enrolling by invitation	Yale University	2024-03-31
NCT03556878	Implementing and Sustaining a Transdiagnostic Sleep and Circadian Treatment	https://ClinicalTrials.gov/show/NCT03556878	Completed	University of California, Berkeley	2018-12-01
NCT03532828	Interaction Between Body Posture and Nocturnal Sleeping Disorders in Dysgnathic Patients	https://ClinicalTrials.gov/show/NCT03532828	Recruiting	Laboratoire de Biomécanique Georges Charpak	2020-12-31
NCT03532269	Validation of the Sleep Assessment Algorithm in the Medical Application Nightly	https://ClinicalTrials.gov/show/NCT03532269	Completed	DreamJay Sp. z o. o.	2017-12-14
NCT03514732	Study to Evaluate Improvements of the Quality of Sleep With NOVANUIT® Triple Action in Healthy Volunteers With Sleep Disorders	https://ClinicalTrials.gov/show/NCT03514732	Completed	Sanofi	2017-07-05
NCT03501004	The Study of Acupuncture on Vascular and Functional Neuroimaging in Parkinson’s Disease Patients With Sleep Disorders	https://ClinicalTrials.gov/show/NCT03501004	Recruiting	Tsinghua University	2020-06-30
NCT03478566	Transcutaneous CO2 Monitoring at Home for Children With Neuromuscular Disease	https://ClinicalTrials.gov/show/NCT03478566	Recruiting	The Hospital for Sick Children	2019-12-31
NCT03478306	Diabetic Retinopathy: Effects of Melatonin Treatment on Visual Functions and Circadian Rhythm	https://ClinicalTrials.gov/show/NCT03478306	Recruiting	Glostrup University Hospital, Copenhagen	2020-10-01
NCT03456219	Determination of Protocol of Nocturnal Food Intake of Shift Workers.	https://ClinicalTrials.gov/show/NCT03456219	Completed	Federal University of Uberlandia	2018-01-11
NCT03453398	Effects of Shift Work on Nurse Staff Health	https://ClinicalTrials.gov/show/NCT03453398	Completed	Istituto Ortopedico Galeazzi	2019-12-30
NCT01259401	Treating Sleep Problems in VA Adult Day Health Care	https://ClinicalTrials.gov/show/NCT01259401	Completed	VA Office of Research and Development	2013-06-30
NCT01256983	Light for Renal Transplant Recipients Having a Sleep-Wake Dysregulation	https://ClinicalTrials.gov/show/NCT01256983	Completed	University of Basel	2013-06-30
NCT01234675	The Effects of Milnacipran on Sleep Disturbance in Fibromyalgia	https://ClinicalTrials.gov/show/NCT01234675	Completed	Cleveland Sleep Research Center	2014-02-28
NCT01234077	Study Comparing In-laboratory Polysomnography Electrocardiogram (PSG ECG) to Simultaneously Recorded In-laboratory ECG on the CPC M1 Device	https://ClinicalTrials.gov/show/NCT01234077	Completed	National Jewish Health	2010-09-30
NCT01220401	Efficacy of a Brief Nightmare Treatment for Veterans	https://ClinicalTrials.gov/show/NCT01220401	Completed	University of Tulsa	2011-08-31
NCT01164592	Substudy on the Mechanistic Plausibility of the Clinical Benefits of Adaptive Servo-ventilation	https://ClinicalTrials.gov/show/NCT01164592	Completed	ResMed	2015-04-30
NCT01163032	Efficacy and Safety of Tasimelteon Compared With Placebo in Totally Blind Subjects With Non-24-Hour Sleep-Wake Disorder	https://ClinicalTrials.gov/show/NCT01163032	Completed	Vanda Pharmaceuticals	2012-11-30
NCT01142258	Trazodone for Sleep Disorders in Alzheimer’s Disease	https://ClinicalTrials.gov/show/NCT01142258	Completed	Brasilia University Hospital	2012-04-30
NCT01124851	Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of ABT-652 in Subjects With Excessive Daytime Sleepiness	https://ClinicalTrials.gov/show/NCT01124851	Completed	Abbott	2011-04-30
NCT01122849	Exploratory Subjective Sleep Study of a Prototype Nasal Dilator	https://ClinicalTrials.gov/show/NCT01122849	Completed	GlaxoSmithKline	2010-02-01
NCT01097382	Sleep Satisfaction and Psychomotor Performance of Adults	https://ClinicalTrials.gov/show/NCT01097382	Completed	Sanofi	2011-04-30
NCT01067222	Efficacy and Safety Study of BF2.649 in the Treatment of Excessive Daytime Sleepiness in Narcolepsy	https://ClinicalTrials.gov/show/NCT01067222	Completed	Bioprojet	2010-07-31
NCT01047930	The Effect of Exercise on Acute Nicotine Withdrawal	https://ClinicalTrials.gov/show/NCT01047930	Completed	University of Pittsburgh	2013-07-31
NCT01030939	Study to Investigate Safety, Tolerability, Pharmacokinetics and Cardiac Function After Repeat Doses of SB-649868 in Healthy-volunteers	https://ClinicalTrials.gov/show/NCT01030939	Completed	GlaxoSmithKline	2010-01-06
NCT01024192	Efficacy and Safety Assessment of ZOlpidem (Stilnox CR) in Patients With Chronic insomNIA	https://ClinicalTrials.gov/show/NCT01024192	Completed	Sanofi	2010-07-31
NCT00994279	Yoga or Educational Wellness Class for Women With Stage I, Stage II, or Stage III Breast Cancer Undergoing Chemotherapy	https://ClinicalTrials.gov/show/NCT00994279	Completed	Wake Forest University Health Sciences	2011-10-14
NCT00992160	Vestipitant 28-day Tolerance Study	https://ClinicalTrials.gov/show/NCT00992160	Completed	GlaxoSmithKline	2009-09-30
NCT00990106	Augmentation Trial of Prazosin for Post-Traumatic Stress Disorder (PTSD)	https://ClinicalTrials.gov/show/NCT00990106	Completed	Seattle Institute for Biomedical and Clinical Research	2013-03-31
NCT00988104	Preventing Long Term Psychiatric Disability Among Those With Major Burn Injuries	https://ClinicalTrials.gov/show/NCT00988104	Completed	Johns Hopkins University	2015-10-15
NCT00972075	Efficacy and Safety of Circadin for Non-24 Hour Sleep-Wake Disorder in Totally Blind Subjects	https://ClinicalTrials.gov/show/NCT00972075	Completed	Neurim Pharmaceuticals Ltd.	2007-08-31
NCT00945230	Actigraphic Measurement of a Neurosurgical Procedure	https://ClinicalTrials.gov/show/NCT00945230	Completed	Child Psychopharmacology Institute	2009-06-30
NCT00942253	Exercise Training in Dialysis Patients With Restless Legs Syndrome (RLS)	https://ClinicalTrials.gov/show/NCT00942253	Completed	University of Thessaly	2010-04-30
NCT00940589	Efficacy of Circadin® 2 mg in Patients With Mild to Moderate Alzheimer Disease Treated With AChE Inhibitor	https://ClinicalTrials.gov/show/NCT00940589	Completed	Neurim Pharmaceuticals Ltd.	2013-02-28
NCT00902330	Cranial Stimulation for Chemotherapy Symptoms in Breast Cancer	https://ClinicalTrials.gov/show/NCT00902330	Completed	Virginia Commonwealth University	2013-05-31
NCT00900159	Effects of Daytime Eszopiclone Administration in Shift Workers	https://ClinicalTrials.gov/show/NCT00900159	Completed	Brigham and Women’s Hospital	2010-01-31
NCT00883740	Effects Of Pregabalin (Lyrica) On Sleep Maintenance In Subjects With Fibromyalgia	https://ClinicalTrials.gov/show/NCT00883740	Completed	Pfizer	2010-06-30
NCT00878553	Study of Sleep-maintenance Activity of 3 Doses of SKP-1041	https://ClinicalTrials.gov/show/NCT00878553	Completed	Somnus Therapeutics, Inc.	2010-12-31
NCT00843843	Sleep Length and Circadian Regulation in Humans	https://ClinicalTrials.gov/show/NCT00843843	Completed	Rush University Medical Center	2014-02-28
NCT00822679	Eszopiclone and Inflammatory Mediators in Patients With Acute Coronary Syndrome	https://ClinicalTrials.gov/show/NCT00822679	Completed	University of Arizona	2009-08-31
NCT03934658	Remote Study of NightWare for PTSD With Nightmares	https://ClinicalTrials.gov/show/NCT03934658	Enrolling by invitation	NightWare	2020-05-15
NCT00814502	Zolpidem CR and Hospitalized Patients With Dementia	https://ClinicalTrials.gov/show/NCT00814502	Completed	Massachusetts General Hospital	2013-12-31
NCT04098848	Intradialytic Exercise on the Fatigue, Sleep Disorder, Arterial Stiffness and Endothelial Function in Uremic Patients	https://ClinicalTrials.gov/show/NCT04098848	Recruiting	Buddhist Tzu Chi General Hospital	2019-07-31
NCT03990909	Pilot Study of BCAA on Sleep	https://ClinicalTrials.gov/show/NCT03990909	Recruiting	Portland VA Medical Center	2024-08-01
NCT02874261	Whole Body Periodic Acceleration on Activity and Sleep In Parkinson’s Disease	https://ClinicalTrials.gov/show/NCT02874261	Completed	New York Institute of Technology	2017-05-31
NCT02797678	Feasibility, Effectiveness and Efficacy of the PowerSleep Device	https://ClinicalTrials.gov/show/NCT02797678	Completed	Philips Respironics	2016-12-31
NCT01591408	EEG Biofeedback Therapy as an Adjunct Treatment for PTSD	https://ClinicalTrials.gov/show/NCT01591408	Completed	United States Naval Medical Center, San Diego	2013-10-31
NCT03537963	Intervention for Sleep Disturbance in HCT Survivors	https://ClinicalTrials.gov/show/NCT03537963	Recruiting	H. Lee Moffitt Cancer Center and Research Institute	2020-12-31
NCT00792584	Patient Preference, Sleep Quality, and Anxiety/Depression: A Randomized Comparison of Etravirine and Efavirenz	https://ClinicalTrials.gov/show/NCT00792584	Completed	University Hospital, Geneva	2008-11-30
NCT00786357	Sleep Enhancement Training Study for Experienced Shiftworkers	https://ClinicalTrials.gov/show/NCT00786357	Completed	University of California, San Francisco	2010-01-31
NCT00786266	Sleep Enhancement Training Study for Novice Shiftworkers	https://ClinicalTrials.gov/show/NCT00786266	Completed	University of California, San Francisco	2010-05-31
NCT00723580	Actigraphic Analysis of Treatment Response	https://ClinicalTrials.gov/show/NCT00723580	Completed	Child Psychopharmacology Institute	2010-07-31
NCT00691626	Cognitive Behavioral Therapy (CBT) for Nightmares in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans	https://ClinicalTrials.gov/show/NCT00691626	Completed	VA Office of Research and Development	2015-01-01
NCT00690196	Tai Chi Effects on Chronic Insomnia in Breast Cancer Survivors: Immune Mechanisms	https://ClinicalTrials.gov/show/NCT00690196	Completed	Jonsson Comprehensive Cancer Center	2012-07-31
NCT00671190	Safety and Efficacy of Ramelteon in Healthy Subjects	https://ClinicalTrials.gov/show/NCT00671190	Completed	Takeda	2005-05-31
NCT00659373	Brain Function in Premenopausal Women Receiving Tamoxifen With or Without Ovarian Function Suppression for Early-Stage Breast Cancer on Clinical Trial IBCSG 24-02	https://ClinicalTrials.gov/show/NCT00659373	Completed	International Breast Cancer Study Group	2014-12-31
NCT00645944	Randomized, Controlled, Double Blind Trial of Eszopiclone for Insomnia Associated With Schizophrenia	https://ClinicalTrials.gov/show/NCT00645944	Completed	Yale University	2011-04-30
NCT00641303	Acupuncture in Reducing Muscle and Bone Symptoms in Women Receiving Letrozole, Exemestane, or Anastrozole for Stage 0, Stage I, Stage II, or Stage III Breast Cancer	https://ClinicalTrials.gov/show/NCT00641303	Completed	University of Maryland, Baltimore	2011-10-31
NCT00631657	A 6-Month Efficacy and Safety Study of Org 50081 in Adult Patients With Chronic Primary Insomnia (21106/P05701/MK-8265-002)	https://ClinicalTrials.gov/show/NCT00631657	Completed	Merck Sharp & Dohme Corp.	2009-11-19
NCT00593736	Efficacy of Ramelteon on Speeding Up Sleep in Subjects With Delayed Sleep Phase Syndrome	https://ClinicalTrials.gov/show/NCT00593736	Completed	Takeda	2008-05-31
NCT00582491	Modafinil, Sleep, and Cognition in Cocaine Dependence	https://ClinicalTrials.gov/show/NCT00582491	Completed	Yale University	2009-02-28
NCT00569166	Three Different Programs of Paced Breathing in Treating Hot Flashes in Women	https://ClinicalTrials.gov/show/NCT00569166	Completed	Mayo Clinic	2010-02-28
NCT00561821	Efficacy and Safety Study of Org 50081 (Esmirtazapine) in Elderly Participants (P05709)	https://ClinicalTrials.gov/show/NCT00561821	Completed	Merck Sharp & Dohme Corp.	2009-12-21
NCT00561574	A Long-Term Safety Study of Org 50081 (Esmirtazapine) in Elderly Outpatients With Chronic Primary Insomnia (176005/P05697/MK-8265-001)	https://ClinicalTrials.gov/show/NCT00561574	Completed	Merck Sharp & Dohme Corp.	2010-02-14
NCT00532493	Cooperative Studies Program #563 - Prazosin and Combat Trauma PTSD	https://ClinicalTrials.gov/show/NCT00532493	Completed	VA Office of Research and Development	2013-02-28
NCT00530556	Insomnia and Daytime Function in Osteoarthritis	https://ClinicalTrials.gov/show/NCT00530556	Completed	Sanofi	2004-06-30
NCT00518986	Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and Depression	https://ClinicalTrials.gov/show/NCT00518986	Completed	Teva Pharmaceutical Industries	2009-03-31
NCT00507546	Functional Melatonin Replacement for Sleep Disruptions in Individuals With Tetraplegia	https://ClinicalTrials.gov/show/NCT00507546	Completed	VA Office of Research and Development	2010-12-31
NCT00506259	Treatment Strategies for Children With Smith-Magenis Syndrome	https://ClinicalTrials.gov/show/NCT00506259	Completed	National Institutes of Health Clinical Center (CC)	2018-05-22
NCT00498563	Effects of Mild Hypobaric Hypoxia on Sleep and Post-sleep Performance	https://ClinicalTrials.gov/show/NCT00498563	Completed	Oklahoma State University Center for Health Sciences	2007-08-31
NCT00494468	Single Dose Pharmacokinetic and Pharmacodynamic Evaluation of Three Different Doses of Zolpidem in Children	https://ClinicalTrials.gov/show/NCT00494468	Completed	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	NA
NCT00490945	Safety and Efficacy of VEC-162 on Circadian Rhythm in Healthy Adult Volunteers	https://ClinicalTrials.gov/show/NCT00490945	Completed	Vanda Pharmaceuticals	2005-03-31
NCT00404456	The Efficacy of Melatonin in Sleep Problems of Hemodialysis and Peritoneal Dialysis Patients	https://ClinicalTrials.gov/show/NCT00404456	Completed	Meander Medical Center	2007-07-31
NCT00397930	Yoga in Treating Sleep Disturbance in Cancer Survivors	https://ClinicalTrials.gov/show/NCT00397930	Completed	University of Rochester	2013-04-30
NCT00390572	Sleep Specialty Consultation: Improving Management of Sleep Disorders	https://ClinicalTrials.gov/show/NCT00390572	Completed	VA Office of Research and Development	2010-07-31
NCT00359216	The Effects of Mometasone Furoate Nasal Spray in Subjects With Sleep-disordered Breathing (SDB) Associated With Perennial Allergic Rhinitis (Study P04726)	https://ClinicalTrials.gov/show/NCT00359216	Completed	Merck Sharp & Dohme Corp.	2008-01-31
NCT00338429	Better Days, Better Nights: Treatment for Sleep Difficulties (Telephone Coached)	https://ClinicalTrials.gov/show/NCT00338429	Completed	IWK Health Centre	2009-05-31
NCT00333619	Non-Pharmacological Interventions on Sleep in Post-Acute Rehabilitation	https://ClinicalTrials.gov/show/NCT00333619	Completed	VA Office of Research and Development	2010-12-31
NCT00313885	Efficacy and Safety of SR46349B in Patients With Sleep Disorders in Fibromyalgia	https://ClinicalTrials.gov/show/NCT00313885	Completed	Sanofi	2005-06-30
NCT00287391	Sleep Disorders and Gastroesophageal Reflux Disease (GERD)	https://ClinicalTrials.gov/show/NCT00287391	Completed	University of North Carolina, Chapel Hill	NA
NCT00283946	A Double-blind, Group-comparison Study Using Zolpidem (Myslee) as a Comparative Drug in Patients With Insomnia	https://ClinicalTrials.gov/show/NCT00283946	Completed	Astellas Pharma Inc	2007-11-30
NCT00261729	Prazosin vs. Paroxetine in Combat Stress Symptoms in OIF/OEF Returnees	https://ClinicalTrials.gov/show/NCT00261729	Completed	VA Office of Research and Development	2007-08-31
NCT00256685	Study Evaluating DVS-233 SR to Treat Vasomotor Systems Associated With Menopause	https://ClinicalTrials.gov/show/NCT00256685	Completed	Wyeth is now a wholly owned subsidiary of Pfizer	NA
NCT00246051	Comprehensive Police Fatigue Management Program	https://ClinicalTrials.gov/show/NCT00246051	Completed	Brigham and Women’s Hospital	2009-12-31
NCT00243971	A Trial to Compare the Efficacy of Rotigotine Transdermal Patch to That of Ropinirole on Early Morning Motor Impairment and Sleep Disorders in Subjects With Early-Stage, Idiopathic Parkinson’s Disease	https://ClinicalTrials.gov/show/NCT00243971	Completed	UCB Pharma	2005-10-31
NCT00243945	A Trial to Evaluate the Effects of Rotigotine Transdermal Patch on Early Morning Motor Impairment and Sleep Disorders Idiopathic Parkinson’s Disease	https://ClinicalTrials.gov/show/NCT00243945	Completed	UCB Pharma	2005-07-31
NCT00238108	Melatonin Supplements for Improving Sleep in Individuals With Hypertension	https://ClinicalTrials.gov/show/NCT00238108	Completed	Brigham and Women’s Hospital	2010-08-31
NCT00236080	Study of the Efficacy and Multiple-Dose Plasma Concentration-Time Profiles of Armodafinil and PROVIGIL	https://ClinicalTrials.gov/show/NCT00236080	Completed	Teva Pharmaceutical Industries	NA
NCT00228553	Extension Study of the Safety and Efficacy of Armodafinil in the Treatment of Patients With Excessive Sleepiness	https://ClinicalTrials.gov/show/NCT00228553	Completed	Teva Pharmaceutical Industries	NA
NCT00207285	Sleep Disorders Management, Health and Safety in Police	https://ClinicalTrials.gov/show/NCT00207285	Completed	Brigham and Women’s Hospital	2010-09-30
NCT00195520	Study Evaluating Totelle® in Menopausal Symptoms and Sexual Function	https://ClinicalTrials.gov/show/NCT00195520	Completed	Wyeth is now a wholly owned subsidiary of Pfizer	NA
NCT00179348	Yoga-Based Rehabilitation Program in Reducing Physical and Emotional Side Effects in Patients With Cancer	https://ClinicalTrials.gov/show/NCT00179348	Completed	Albert Einstein College of Medicine	2016-07-20
NCT00177216	Characteristics of Sleep Patterns in Young Adults With and Without Insomnia	https://ClinicalTrials.gov/show/NCT00177216	Completed	University of Pittsburgh	2008-05-31
NCT00174174	Provigil (Modafinil) Study by Taiwan Biotech Co.	https://ClinicalTrials.gov/show/NCT00174174	Completed	National Taiwan University Hospital	NA
NCT00149747	The Effectiveness of Regular Exercise on Improving Sleep in Older Adults	https://ClinicalTrials.gov/show/NCT00149747	Completed	Stanford University	2003-09-30
NCT00132821	Impact of Smoking Cessation on Sleep - 5	https://ClinicalTrials.gov/show/NCT00132821	Completed	National Institute on Drug Abuse (NIDA)	2009-05-31
NCT00120484	Effects of Vitamin B12 on the Body’s Internal Clock	https://ClinicalTrials.gov/show/NCT00120484	Completed	Brigham and Women’s Hospital	2007-12-31
NCT00084669	Venlafaxine With or Without Zolpidem in Treating Hot Flashes and Associated Sleep Disorders in Women With Breast Cancer OR at High Risk for Developing Breast Cancer	https://ClinicalTrials.gov/show/NCT00084669	Completed	Massachusetts General Hospital	2007-10-31
NCT00080288	Safety/Efficacy Study With Armodafinil (CEP-10953) in Treatment of Excessive Sleepiness Associated With Chronic SWSD	https://ClinicalTrials.gov/show/NCT00080288	Completed	Teva Pharmaceutical Industries	NA
NCT00078312	Armodafinil (CEP-10953) for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep Disorder	https://ClinicalTrials.gov/show/NCT00078312	Completed	Teva Pharmaceutical Industries	2006-07-31
NCT00075842	(Valerian) for Improving Sleep in Patients With Cancer Receiving Adjuvant Therapy	https://ClinicalTrials.gov/show/NCT00075842	Completed	Alliance for Clinical Trials in Oncology	2007-03-31
NCT00819208	Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer	https://ClinicalTrials.gov/show/NCT00819208	Recruiting	Canadian Cancer Trials Group	2029-12-15
NCT00199446	Study of Istradefylline (KW-6002) for the Treatment of Restless Legs Syndrome	https://ClinicalTrials.gov/show/NCT00199446	Completed	Kyowa Kirin Pharmaceutical Development, Inc.	2006-08-31
NCT00013182	Effect of Activity on Sleep of Cognitively-Impaired Veterans	https://ClinicalTrials.gov/show/NCT00013182	Completed	VA Office of Research and Development	NA
NCT00000380	Growth Hormone Releasing Hormone (GHRH) Treatment for Age-Related Sleep Disturbances	https://ClinicalTrials.gov/show/NCT00000380	Completed	University of Washington	2007-07-31

Observational Studiess

#If less then 500 studies

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT00071786	Family Study of Affective and Anxiety Spectrum Disorders	https://ClinicalTrials.gov/show/NCT00071786	Recruiting	National Institutes of Health Clinical Center (CC)	NA
NCT03332407	Does Preoperative Sleep Quality Affect the Postoperative Emergence Delirium in Children Undergoing Strabismus Surgery	https://ClinicalTrials.gov/show/NCT03332407	Completed	Pusan National University Hospital	2017-09-30
NCT03320382	Multiple Breath Washout, a Clinimetric Dataset	https://ClinicalTrials.gov/show/NCT03320382	Recruiting	Imperial College London	2021-03-31
NCT03224455	Environmental Assessment of Sleep in Youth	https://ClinicalTrials.gov/show/NCT03224455	Recruiting	Boston Children’s Hospital	2022-12-01
NCT03099954	Withings Pulse Wave Velocity and Blood Pressure Study	https://ClinicalTrials.gov/show/NCT03099954	Completed	Scripps Translational Science Institute	2017-08-01
NCT03054116	Airflow Perturbation Device (APD) for the Evaluation of Pulmonary and Sleep Disorders	https://ClinicalTrials.gov/show/NCT03054116	Completed	Walter Reed National Military Medical Center	2014-08-31
NCT02997319	Shift Work, Heredity, Insulin, and Food Timing Study	https://ClinicalTrials.gov/show/NCT02997319	Recruiting	Massachusetts General Hospital	2020-07-31
NCT02981238	Phytotherapy Strategy for Sleep Disorders Related to Anxiety With a Combination of Eschscholtzia and Valerian Extracts	https://ClinicalTrials.gov/show/NCT02981238	Completed	Pileje	2017-01-12
NCT02901860	Shift Work and Risk of Cardio-vascular Disease	https://ClinicalTrials.gov/show/NCT02901860	Completed	University of Chicago	2014-12-31
NCT02585609	Sleep Quality in Patients With Advanced Cancer	https://ClinicalTrials.gov/show/NCT02585609	Completed	Norwegian University of Science and Technology	2017-03-10
NCT02522195	Meal Distribution Across the Day in Female Nurses Working Shifts	https://ClinicalTrials.gov/show/NCT02522195	Completed	Federal University of Uberlandia	2012-11-30
NCT02369705	Validation of Ambulatory Sleep Test (WP200/U) Compared In-lab Sleep Testing in Cardiac Subjects	https://ClinicalTrials.gov/show/NCT02369705	Completed	Itamar-Medical, Israel	2016-06-30
NCT02260297	A Study of Wrist Actigraphy in Overweight and Obese Adults With Sleep Disorders	https://ClinicalTrials.gov/show/NCT02260297	Completed	Shanghai Jiao Tong University School of Medicine	2014-10-31
NCT02231398	nuMoM2b Heart Health Study	https://ClinicalTrials.gov/show/NCT02231398	Active, not recruiting	RTI International	2020-04-30
NCT02188498	Electrocardiography Data Analysis in Sleep Disorders	https://ClinicalTrials.gov/show/NCT02188498	Completed	Weill Medical College of Cornell University	2017-11-30
NCT02111408	Stroke - Sleep Disorders, Dysfunction of the Autonomic Nervous System and Depression	https://ClinicalTrials.gov/show/NCT02111408	Active, not recruiting	Glostrup University Hospital, Copenhagen	2017-02-28
NCT01280097	Study of Sleep and Delirium in the Intensive Care Unit (ICU)	https://ClinicalTrials.gov/show/NCT01280097	Completed	University of California, San Francisco	2012-11-30
NCT03083405	Selected Disorders and Sleep Bruxism	https://ClinicalTrials.gov/show/NCT03083405	Enrolling by invitation	Wroclaw Medical University	2020-09-30
NCT01929447	Evaluation of WP200 With the Unified Probe (WP200U)	https://ClinicalTrials.gov/show/NCT01929447	Completed	Itamar-Medical, Israel	2014-09-30
NCT01881854	Sleep Wake and Melatonin Pattern in Craniopharyngioma	https://ClinicalTrials.gov/show/NCT01881854	Completed	Rigshospitalet, Denmark	2012-09-30
NCT04406324	COVID-19: Respiratory and Sleep Follow-up	https://ClinicalTrials.gov/show/NCT04406324	Recruiting	University Hospital, Grenoble	2021-03-05
NCT01667588	Sleep Disorders in Pediatric Dialysis	https://ClinicalTrials.gov/show/NCT01667588	Completed	The Hospital for Sick Children	2014-03-31
NCT01570738	Validation of Home Sleep Testing (WP) Compared to an Overnight Sleep Testing in the Sleep Laboratory	https://ClinicalTrials.gov/show/NCT01570738	Recruiting	Itamar-Medical, Israel	2020-08-31
NCT01528462	Sleep Disorders Managed and Assessed Rapidly in Transient Ischemic Attack (TIA) and In Early Stroke	https://ClinicalTrials.gov/show/NCT01528462	Completed	Sunnybrook Health Sciences Centre	2013-09-30
NCT01465971	Monitoring of the Cerebral Tissue Oxygenation and Perfusion in the Adapting Climber During Sleep in High Altitude	https://ClinicalTrials.gov/show/NCT01465971	Completed	Goethe University	2011-12-31
NCT01463839	Sleep Disorder and Oral Habits in Children	https://ClinicalTrials.gov/show/NCT01463839	Completed	University of Nove de Julho	2010-10-31
NCT01371669	Screening for Sleep Hypoxemia in Pulmonary Arterial Hypertension	https://ClinicalTrials.gov/show/NCT01371669	Completed	Assistance Publique - Hôpitaux de Paris	2011-07-31
NCT01358474	Detecting Dopaminergic Deficits in Individuals At-risk for Parkinsonism	https://ClinicalTrials.gov/show/NCT01358474	Completed	University of Minnesota	2014-10-31
NCT01343446	Sleep Impairment and Coping Style in Diabetes	https://ClinicalTrials.gov/show/NCT01343446	Completed	Istanbul University	2011-03-31
NCT04416789	Exercise Intervention for Sleep in Neurodevelopmental Disorders	https://ClinicalTrials.gov/show/NCT04416789	Completed	Guy’s and St Thomas’ NHS Foundation Trust	2020-01-06
NCT04340583	Subjective Sleep Quality and Sleep Disorders in Patients With Severe Asthma	https://ClinicalTrials.gov/show/NCT04340583	Recruiting	Istituti Clinici Scientifici Maugeri SpA	2022-03-31
NCT04331821	READ-ASV Registry - Phase II	https://ClinicalTrials.gov/show/NCT04331821	Recruiting	ResMed	2021-03-31
NCT04249011	WatchPAT Compared to PSG at 8500’	https://ClinicalTrials.gov/show/NCT04249011	Completed	Itamar-Medical, Israel	2018-08-14
NCT04232267	Analysis of Sleep Study Data to Assess Depressive Burden	https://ClinicalTrials.gov/show/NCT04232267	Recruiting	Medibio Limited	2021-01-31
NCT04214561	Relationship Between Selected Parameters and Bruxism	https://ClinicalTrials.gov/show/NCT04214561	Enrolling by invitation	Wroclaw Medical University	2020-12-31
NCT04201392	Sleep in Psychiatric Inpatients	https://ClinicalTrials.gov/show/NCT04201392	Recruiting	University of Zurich	2020-03-31
NCT04161612	Sleep Quality & Spinal Cord Injury	https://ClinicalTrials.gov/show/NCT04161612	Completed	Istanbul Physical Medicine Rehabilitation Training and Research Hospital	2019-12-12
NCT04061226	Relationship Between Normal-weight Central Obesity and Obstructive Sleep Apnea	https://ClinicalTrials.gov/show/NCT04061226	Recruiting	St. Anne’s University Hospital Brno, Czech Republic	2019-12-31
NCT04032561	Relationship Between HbA1c Level, Sleep Quality and Sleep Duration	https://ClinicalTrials.gov/show/NCT04032561	Recruiting	University of Hertfordshire	2019-09-06
NCT04009902	Evaluation of Depression and Sleep Disorders in Endometriosis Patients	https://ClinicalTrials.gov/show/NCT04009902	Completed	Kanuni Sultan Suleyman Training and Research Hospital	2020-05-03
NCT03976479	Body Composition, Nutritional and Cardiovascular Status and Lifestyle Factors of Adults Who Are on Plant-Based Diet	https://ClinicalTrials.gov/show/NCT03976479	Completed	Barbara Jakše s.p.	2019-07-30
NCT03903263	Sleep Disturbances in Dermatology Patients	https://ClinicalTrials.gov/show/NCT03903263	Completed	University Hospital, Basel, Switzerland	2019-01-31
NCT03786120	The Efficacy of Lower Dose Zolpidem for Achieving Satisfactory Sleep in Women With Disordered Sleep	https://ClinicalTrials.gov/show/NCT03786120	Recruiting	Rhode Island Hospital	2019-07-31
NCT03763435	The Effects of Pregnancy Classes and Contributing Factors to Postpartum Depression	https://ClinicalTrials.gov/show/NCT03763435	Recruiting	Bartin State Hospital	2019-06-15
NCT03763071	Sleep Disturbances in the 2nd and 3rd Trimester	https://ClinicalTrials.gov/show/NCT03763071	Recruiting	Bartin State Hospital	2019-07-08
NCT03760159	Minimally Invasive Detection of a Sleep Apnoea	https://ClinicalTrials.gov/show/NCT03760159	Enrolling by invitation	Erasme University Hospital	2019-04-01
NCT03737552	Sleep Patterns in Children and Adolescents With ADHD	https://ClinicalTrials.gov/show/NCT03737552	Active, not recruiting	Assiut University	2020-12-31
NCT03685994	Sleep Disorders After TIPS	https://ClinicalTrials.gov/show/NCT03685994	Recruiting	West China Hospital	2019-08-31
NCT03651492	Effects of Nocturnal Hypertension on Sleep Quality in Renal Transplant Recipients	https://ClinicalTrials.gov/show/NCT03651492	Recruiting	Federico II University	2019-06-01
NCT03644758	Assessment of the Quality of Sleep and Sleep Disorders Among the Professional and Volunteer Firefighters of Loire	https://ClinicalTrials.gov/show/NCT03644758	Completed	Centre Hospitalier Universitaire de Saint Etienne	2019-05-14
NCT03499132	Influence of Different Anesthetic Procedures on Sleep Disorder Breathing	https://ClinicalTrials.gov/show/NCT03499132	Completed	St. Anne’s University Hospital Brno, Czech Republic	2019-12-31
NCT03468400	Evaluation of the Reliability and Validity of a Diagnostic Sleep Disorders Questionnaire	https://ClinicalTrials.gov/show/NCT03468400	Active, not recruiting	Dayzz Live Well Ltd.	2019-04-01
NCT01229501	Fat Biology, Sleep Disorders, and Cardiovascular Disease	https://ClinicalTrials.gov/show/NCT01229501	Completed	Mayo Clinic	2016-02-29
NCT01195558	Patient Registry of Blind Subjects With Sleep-related Problems	https://ClinicalTrials.gov/show/NCT01195558	Recruiting	Vanda Pharmaceuticals	2030-04-30
NCT01184235	Multidimensional Measurement of Psychopharmacological Treatment Response	https://ClinicalTrials.gov/show/NCT01184235	Completed	Child Psychopharmacology Institute	2011-08-31
NCT01125605	PASCONAL NERVENTROPFEN in the Treatment of Nervous Diseases	https://ClinicalTrials.gov/show/NCT01125605	Completed	Pascoe Pharmazeutische Praeparate GmbH	2010-10-31
NCT00830115	Pantoprazole 20/40 mg in the Treatment of Symptomatic Reflux Disease With Focus on Sleep Disorders	https://ClinicalTrials.gov/show/NCT00830115	Completed	Nycomed	2009-05-31
NCT03793699	Evaluation of the Links Between Sleep Disorders and the Risk of Suicide Attempt	https://ClinicalTrials.gov/show/NCT03793699	Recruiting	University Hospital, Lille	2022-12-31
NCT04007042	Validation of a Short Questionnaire (SSI) for Sleep Disorders in Patients With Alcohol	https://ClinicalTrials.gov/show/NCT04007042	Completed	Centre Hospitalier Universitaire de NÄ«mes	2013-01-15
NCT03834792	Adverse Long-term Consequences of Sleep Disordered Breathing: The TOH Sleep Database	https://ClinicalTrials.gov/show/NCT03834792	Active, not recruiting	Ottawa Hospital Research Institute	2025-12-31
NCT00692471	Sleep Actigraphy in Postural Tachycardia Syndrome (POTS)	https://ClinicalTrials.gov/show/NCT00692471	Active, not recruiting	Vanderbilt University Medical Center	2021-12-31
NCT00691080	Understanding Sleep Problems in Children With Autism Spectrum Disorder	https://ClinicalTrials.gov/show/NCT00691080	Completed	Baylor College of Medicine	2011-09-30
NCT00688142	Sleepiness and Brain Function: The Effect of Armodafinil in Shift Work Sleep Disorder	https://ClinicalTrials.gov/show/NCT00688142	Completed	Henry Ford Health System	2010-03-31
NCT00800397	Evaluation of the Noga System: Detecting of Respiratory Related Sleep Disorders in Cardiac Patients	https://ClinicalTrials.gov/show/NCT00800397	Completed	WideMed LTD.	2008-12-31
NCT00562094	Efficacy of Pantoprazole in Patients Older Than 12 Years With Reflux Associated Sleep Disorders (PULS)	https://ClinicalTrials.gov/show/NCT00562094	Completed	Nycomed	2009-04-30
NCT00507481	Evaluation of Risk Factors of Sleep Quality in Intensive Care Unit	https://ClinicalTrials.gov/show/NCT00507481	Completed	University of Turin, Italy	NA
NCT00346554	To Study the Prevalence of Insomnia in Geriatric COPD Patients Who Are Enrolled in a Pulmonary Rehabilitation Program.	https://ClinicalTrials.gov/show/NCT00346554	Completed	Hackensack Meridian Health	2008-05-31
NCT00268502	Quality of Life in African-American or Caucasian Female Breast Cancer Survivors	https://ClinicalTrials.gov/show/NCT00268502	Completed	Indiana University	2007-11-30
NCT00246454	Circadian Rhythms and Sleep in Familial DSPS and ASPS	https://ClinicalTrials.gov/show/NCT00246454	Recruiting	Northwestern University	2025-09-30
NCT00203840	Pediatric Sleep Questionnaire: Normalization and Validation Study	https://ClinicalTrials.gov/show/NCT00203840	Completed	University of Chicago	2016-04-30
NCT00203827	Pediatric Sleep Questionnaire: Use for Collection of Clinical Data	https://ClinicalTrials.gov/show/NCT00203827	Completed	University of Chicago	2011-09-30
NCT00178568	Reducing Caregiver Stress and Sleep Disturbances in Patients With Progressive Dementia	https://ClinicalTrials.gov/show/NCT00178568	Completed	University of Pittsburgh	2008-11-30
NCT00172471	The Relationship Between Sleep Disorders and Cytokine Levels Among Hemodialysis and Peritoneal Dialysis Patients	https://ClinicalTrials.gov/show/NCT00172471	Completed	National Taiwan University Hospital	NA
NCT00163670	The Impact of Sleep Disorders on Motor Vehicle Accidents	https://ClinicalTrials.gov/show/NCT00163670	Completed	Bayside Health	2006-07-31
NCT00001546	Circadian Regulation of Sleep in Habitual Short Sleepers and Long Sleepers	https://ClinicalTrials.gov/show/NCT00001546	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00005557	Epidemiology of Sleep-Disordered Breathing in Adults	https://ClinicalTrials.gov/show/NCT00005557	Active, not recruiting	University of Wisconsin, Madison	2023-04-30
NCT00001664	Sleep Disorders of Patients With Diseases of the Nervous System	https://ClinicalTrials.gov/show/NCT00001664	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00001659	Consequences of Conjugal Bereavement in Adults	https://ClinicalTrials.gov/show/NCT00001659	Completed	National Institutes of Health Clinical Center (CC)	NA

Registries

#If less then 500 registries

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03254836	Sleep and Survival in Colorectal Cancer	https://ClinicalTrials.gov/show/NCT03254836	Active, not recruiting	Zealand University Hospital	2018-07-31
NCT02752139	Cerebral Hemodynamics in Sleep Disorders	https://ClinicalTrials.gov/show/NCT02752139	Completed	First Hospital of Jilin University	2018-08-31
NCT01792583	The Nuvigil and Provigil Pregnancy Registry	https://ClinicalTrials.gov/show/NCT01792583	Recruiting	Teva Pharmaceutical Industries	2027-07-30
NCT04116827	Sleep and Activity Patterns in Pre-menopausal Breast Cancer Patients on Tamoxifen Using a Wrist-worn Internet of Things Device	https://ClinicalTrials.gov/show/NCT04116827	Recruiting	Samsung Medical Center	2020-12-31
NCT03614377	DEvice-Detected CArdiac Tachyarrhythmic Events and Sleep-disordered Breathing (DEDiCATES)	https://ClinicalTrials.gov/show/NCT03614377	Recruiting	Samsung Medical Center	2019-04-30
NCT03535636	Sleep Architecture in Refugees Diagnosed With PTSD	https://ClinicalTrials.gov/show/NCT03535636	Active, not recruiting	Mental Health Services in the Capital Region, Denmark	2020-12-31